The neurophysiology simulation research lab is engaged with electromyography (EMG), nerve conduction velocity (NCV) and Action potential experiments.
EMG involves inserting a fine needle into a muscle to compare the amount of electrical activity present when muscles are at rest and when they contract. EMG tests can help differentiate between muscle and nerve disorders.
NCV tests can precisely measure the degree of damage in larger nerve fibers, revealing whether symptoms are being caused by degeneration of the myelin sheath or the axon. During this test, a probe electrically stimulates a nerve fiber, which responds by generating its own electrical impulse. An electrode placed further along the nerve’s pathway measures the speed of impulse transmission along the axon. Slow transmission rates and impulse blockage tend to indicate damage to the myelin sheath, while a reduction in the strength of impulses is a sign of axonal degeneration.
The primary goal of our research is to identify new drugs for treating some kinds of neuropathies. One of the subjects of our investigations is:
The effects of progesterone on neuropathic pain responses in an experimental animal model for peripheral neuropathy in the rat: a behavioral and electrophysiological study.
M. Jarrahi, PhD, Assistant Prof. in Neuroscience